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Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite

Organic hydroperoxide resistance (Ohr) enzymes are unique Cysbased, lipoyl-dependent peroxidases. Here, we investigated the involvement of Ohr in bacterial responses toward distinct hydroper-oxides...

Organic hydroperoxide resistance gene encodes a thiol-dependent peroxidase

ohr (organic hydroperoxide resistance gene) is present in several species of bacteria, and its deletion renders cells specifically sensitive to organic peroxides. The goal of this work was to deter...

Structural and Biochemical Characterization of Peroxiredoxin Q beta from Xylella fastidiosa catalytic mechanism and high reactivity

The phytopathogenic bacterium Xylella fastidiosa is the etiological agent of various plant diseases. To survive under oxidative stress imposed by the host, microorganisms express antioxidant protei...

Structural insights on the efficient catalysis of hydroperoxide reduction by Ohr: Crystallographic and molecular dynamics approaches

Organic hydroperoxide resistance (Ohr) enzymes are highly efficient Cys-based peroxidases that play central roles in bacterial response to fatty acid hydroperoxides and peroxynitrite, two oxidants ...

Transcriptome Analysis of the Phytobacterium Xylella fastidiosa Growing under Xylem- Based Chemical Conditions

Xylella fastidiosa is a xylem-limited bacterium responsible for important plant diseases, like citrus-variegated chlorosis (CVC) and grapevine Pierce's disease (PD). Interestingly, in vitro growth ...