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Collaborative research networks work
Brazil was heralded for completion of the first genome sequence of a plant pathogen following the development of a virtual research center - a collaborative network of laboratories throughout the s...
Evolutionary change - patterns and processes
The present review considered: (a) the factors that conditioned the early transition from non-life to life; (b) genome structure and complexity in prokaryotes, eukaryotes, and organelles; (c) compa...
Expanding Role of Type II Secretion in Bacterial Pathogenesis and Beyond
Type II secretion (T2S) is one means by which Gram-negative pathogens secrete proteins into the extracellular milieu and/or host organisms. Based upon recent genome sequencing, it is clear that T2S...
Initial biochemical and functional characterization of a 5 '-nucleotidase from Xylella fastidiosa related to the human cytosolic 5 '-nucleotidase I
The 5'-nucleotidases constitute a ubiquitous family of enzymes that catalyze either the hydrolysis or the transfer of esterified phosphate at the 5' position of nucleoside monophosphates. These enz...
Molecular modeling databases: A new way in the search of protein targets for drug development
DBMODELING is a relational database of annotated comparative protein structure models and their metabolic pathway characterization. It is focused on enzymes identified in the genomes of Mycobacteri...
Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite
Organic hydroperoxide resistance (Ohr) enzymes are unique Cysbased, lipoyl-dependent peroxidases. Here, we investigated the involvement of Ohr in bacterial responses toward distinct hydroper-oxides...
Ribosome Display of Combinatorial Antibody Libraries Derived from Mice Immunized with Heat-Killed Xylella fastidiosa and the Selection of MopB-Specific Single-Chain Antibodies
Pierce's disease is a devastating lethal disease of Vitus vinifera grapevines caused by the bacterium Xylella fastidiosa. There is no cure for Pierce's disease, and control is achieved predominantl...
Sonication-Assisted Production of Fosetyl-Al Nanocrystals: Investigation of Human Toxicity and In Vitro Antibacterial Efficacy againstXylella fastidiosa
Recently, there is a growing demand in sustainable phytopathogens control research. Nanotechnology provides several tools such as new pesticides formulations, antibacterial nanomaterials and smar...
The crystal structure of the cysteine protease Xylellain from Xylella fastidiosa reveals an intriguing activation mechanism
Xylella fastidiosa is responsible for a wide range of economically important plant diseases. We report here the crystal structure and kinetic data of Xylellain, the first cysteine protease characte...
